Which body system is most likely to be injured if someone is burned over?

The respiratory system is particularly vulnerable in the case of burns, especially if the injury involves inhalation of hot air or smoke. When a person is burned over, especially in a wildland fire scenario, they may be exposed to extreme temperatures, hazardous chemicals, and smoke inhalation. These factors can lead to damage in the airways, lung tissues, and overall respiratory function, potentially resulting in complications like bronchospasm, pulmonary edema, or respiratory failure.

Inhalation injuries can significantly impair oxygen exchange, making the respiratory system the body system at the highest risk during burn incidents. While other systems, such as the cardiovascular or musculoskeletal systems, can also be affected by burns, the respiratory system's role in sustaining life and its immediate response to the thermal and chemical injuries makes it paramount in this context.